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Title page for ETD etd-0321102-085124


Type of Document PHD
Author Hartmann, Steven L
Author's Email Address steve.hartmann@vanderbilt.edu
URN etd-0321102-085124
Title Intraoperative identification and display of cortical brain function
Degree PhD
Department Biomedical Engineering
Advisory Committee
Advisor Name Title
Benoit M. Dawant Committee Co-Chair
Robert L. Galloway Committee Co-Chair
J. Michael Fitzpatrick Committee Member
Michael I. Miga Committee Member
Peter E. Konrad Committee Member
Keywords
  • registration
  • image-guided surgery
  • brain function
Date of Defense 2002-05-10
Availability unrestricted
Abstract
The objective of this research was to design and develop a system capable of displaying cortical brain function during image-guided neurosurgery. Brain function was determined using a cortical stimulator, classified according to function type, and displayed along with pre-operative tomographic and rendered images of the brain. In addition to displaying brain function acquired from the patient undergoing surgery, a probabilistic map of functional information acquired from a database or previous patients may also be displayed. This information is stored in an atlas coordinate system and can be mapped to the patient's coordinate system for display during surgery.

The entire system was tested and evaluated during three human neurosurgery procedures. Functional information corresponding to speech, motor, and sensory regions was identified and displayed during surgery. This data was then mapped to a common reference database using a non-linear registration algorithm to evaluate the feasibility of using this system to create a functional atlas of the human brain.

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