Type of Document	PHD
Author	Hartmann, Steven L
Author's Email Address	steve.hartmann@vanderbilt.edu
URN	etd-0321102-085124
Title	Intraoperative identification and display of cortical brain function
Degree	PhD
Department	Biomedical Engineering
Advisory Committee	Advisor Name Title Benoit M. Dawant Committee Co-Chair Robert L. Galloway Committee Co-Chair J. Michael Fitzpatrick Committee Member Michael I. Miga Committee Member Peter E. Konrad Committee Member
Keywords	registration image-guided surgery brain function
Date of Defense	2002-05-10
Availability	unrestricted
Abstract The objective of this research was to design and develop a system capable of displaying cortical brain function during image-guided neurosurgery. Brain function was determined using a cortical stimulator, classified according to function type, and displayed along with pre-operative tomographic and rendered images of the brain. In addition to displaying brain function acquired from the patient undergoing surgery, a probabilistic map of functional information acquired from a database or previous patients may also be displayed. This information is stored in an atlas coordinate system and can be mapped to the patient's coordinate system for display during surgery. The entire system was tested and evaluated during three human neurosurgery procedures. Functional information corresponding to speech, motor, and sensory regions was identified and displayed during surgery. This data was then mapped to a common reference database using a non-linear registration algorithm to evaluate the feasibility of using this system to create a functional atlas of the human brain.
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