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Title page for ETD etd-04032006-113734


Type of Document Master's Thesis
Author Sanders, David L
URN etd-04032006-113734
Title Detecting Asthma Exacerbations in a Pediatric Emergency Department
Degree Master of Science
Department Biomedical Informatics
Advisory Committee
Advisor Name Title
Dominik Aronsky Committee Chair
Kevin B Johnson Committee Member
Neal R Patel Committee Member
Keywords
  • medical informatics
  • asthma
  • Asthma in children -- Diagnosis
  • Pediatric emergency services -- Data processing
  • Respiratory emergencies -- Data processing
Date of Defense 2006-02-24
Availability unrestricted
Abstract
This thesis describes the development and evaluation of a computerized algorithm for detecting patients with acute asthma exacerbations who present to a pediatric emergency department (ED). A rule-based algorithm was designed to collect patient information from the computerized patient record at the time of ED triage. We confirmed the feasibility of this approach through a retrospective analysis. The algorithm was then implemented in the pediatric ED as a real-time asthma detection system. Its performance was evaluated prospectively during a two-month study period on over 3,500 ED patients, of which 342 had an asthma exacerbation. The system was able detect patients presenting with acute asthma with high accuracy. Sensitivity was 71.6%, specificity was 97.8%, positive predictive value was 77.0%, and negative predictive value was 97.1%.

This research could be applied to detect and automatically initiate guidelines for the management of asthma in eligible patients, and could serve as a model for detecting other conditions which are managed by standardized guidelines in the ED.

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