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Title page for ETD etd-03292010-210044


Type of Document Master's Thesis
Author Oliver, Kevin Michael
URN etd-03292010-210044
Title Progress towards the natural products Baumycin and the alpha-2,3-sialyl T antigen
Degree Master of Science
Department Chemistry
Advisory Committee
Advisor Name Title
Brain Bachmann Committee Member
Gary Sulikowski Committee Member
Keywords
  • daunomycin
  • sialyl t antigen
  • baumycin
Date of Defense 2010-05-14
Availability unrestricted
Abstract
This thesis covers the work done in our lab towards the synthesis of two unique natural products. The first project is the work towards Baumycin in an attempt to elucidate some structural information. We have worked on a model system and attempted some preliminary glycosylations of related compound daunomycin. The second project entails the work done thus far in the synthesis of the 2,3 sT antigen in order to use it as a probe for the cell surface protein GspB. The work done with GspB is an attempt to identify the active site of the protein.
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